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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRAK1BP1
All Species:
14.85
Human Site:
S221
Identified Species:
40.83
UniProt:
Q5VVH5
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VVH5
NP_001010844.1
260
29106
S221
Q
I
D
D
H
Q
S
S
R
L
S
S
S
L
T
Chimpanzee
Pan troglodytes
XP_518596
187
20685
V154
E
K
L
D
S
S
V
V
I
S
P
P
Q
F
Y
Rhesus Macaque
Macaca mulatta
XP_001113735
260
28898
S221
Q
I
D
D
H
Q
S
S
R
L
S
S
S
L
T
Dog
Lupus familis
XP_539013
305
33692
S266
Q
I
D
D
L
Q
S
S
R
L
S
S
S
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9ESJ7
259
28842
S220
Q
T
D
D
H
Q
L
S
R
L
P
G
T
L
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419874
359
39520
S319
G
H
I
D
S
H
L
S
N
S
P
D
S
L
T
Frog
Xenopus laevis
Q08AV8
245
26790
H211
Q
A
E
S
S
Q
A
H
Q
S
I
Q
S
K
I
Zebra Danio
Brachydanio rerio
Q501X6
249
28044
S214
S
Q
Q
D
A
S
G
S
P
L
T
L
H
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783672
318
35338
G277
P
A
A
A
Q
E
T
G
N
G
Q
E
G
P
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.6
96.1
76.7
N.A.
82.3
N.A.
N.A.
N.A.
42.6
55
40.7
N.A.
N.A.
N.A.
N.A.
34.5
Protein Similarity:
100
70.3
96.9
80
N.A.
87.3
N.A.
N.A.
N.A.
54.3
70.3
60
N.A.
N.A.
N.A.
N.A.
51.8
P-Site Identity:
100
6.6
100
93.3
N.A.
66.6
N.A.
N.A.
N.A.
33.3
20
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
13.3
100
93.3
N.A.
73.3
N.A.
N.A.
N.A.
33.3
40
26.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
23
12
12
12
0
12
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
45
78
0
0
0
0
0
0
0
12
0
0
0
% D
% Glu:
12
0
12
0
0
12
0
0
0
0
0
12
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% F
% Gly:
12
0
0
0
0
0
12
12
0
12
0
12
12
0
0
% G
% His:
0
12
0
0
34
12
0
12
0
0
0
0
12
0
0
% H
% Ile:
0
34
12
0
0
0
0
0
12
0
12
0
0
0
12
% I
% Lys:
0
12
0
0
0
0
0
0
0
0
0
0
0
12
0
% K
% Leu:
0
0
12
0
12
0
23
0
0
56
0
12
0
56
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% M
% Asn:
0
0
0
0
0
0
0
0
23
0
0
0
0
0
0
% N
% Pro:
12
0
0
0
0
0
0
0
12
0
34
12
0
23
0
% P
% Gln:
56
12
12
0
12
56
0
0
12
0
12
12
12
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
45
0
0
0
0
0
12
% R
% Ser:
12
0
0
12
34
23
34
67
0
34
34
34
56
0
0
% S
% Thr:
0
12
0
0
0
0
12
0
0
0
12
0
12
0
56
% T
% Val:
0
0
0
0
0
0
12
12
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _